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What is Humatrope 72iu and what is it used for?
Your medicine or your caregiver’s medicine is called Humatrope. It contains human growth hormone, also called somatropin. Humatrope is made by a special process known as recombinant DNA technology. It has the same structure as the growth hormone that your body makes.
Growth hormone regulates the growth and development of cells in your body. When the growth of cells in the spine and long bones of the legs is stimulated, it causes an increase in height.
In cases of growth hormone deficiency, growth hormone also increases bone mineral content, the number and size of muscle cells, and reduces body fat deposits.
Humatrope 72iu is used to
- Treatment of children and adolescents with any of the following growth disturbances:
- Insufficient production of growth hormone (growth hormone deficiency),
- Absence of all or some X-sex chromosomes in women of short stature (Turner syndrome),
- A disease in which the kidneys are damaged (chronic problems with the way the kidneys work) in children with delayed growth before puberty,
- Short stature at birth (SGA = small for gestational age) who have not regained their height corresponding to 4 years of age or later,
- An alteration of a gene called SHOX (SHOX deficiency).
- Treatment of adults who have confirmed growth hormone deficiency beginning well in childhood or adulthood.
How to use Humatrope 72iu?
Follow exactly the instructions of administration of this medicine indicated by your doctor. If in doubt, consult your doctor or pharmacist again.
- Always make sure you use the cartridge with the strength that your doctor has prescribed (6 mg, 12 mg or 24 mg strength) and the correct CE marked Humatrope pen injection system. Never use cartridges of other medications in your Humatrope 72iu pen.
- Each Humatrope cartridge comes with a syringe containing a diluent (solvent for solution for injection) for reconstitution (mixing and preparing the solution for injection).
- Do not mix or inject Humatrope until you have received sufficient training from your doctor or other qualified healthcare professionals.
- For detailed instructions on how to prepare and inject Humatrope, see the section “How to inject Humatrope” at the end of this leaflet. You should only mix Humatrope with the diluent provided. Never mix it with anything else unless your doctor tells you to.
- After reconstitution, Humatrope should be injected into the fatty tissue just under the skin using a short needle and a pen injection system.
- Injection sites should be varied to avoid local reduction and hardening of fatty tissue under the skin (lipoatrophy).
- After mixing Humatrope 72iu, do not leave it out of the refrigerator for more than 30 minutes each day.
- Keep your pen with the rest of Humatrope in the refrigerator. Do not use leftover Humatrope 28 days after mixing.
Humatrope 72iu Dosage Guide
Your doctor will indicate your dosage and administration schedule. Do not change your dose without checking with your doctor.
Humatrope treatment is usually a long-term treatment; Your dose may need to be adjusted by your doctor over time depending on your body weight and response to treatment. In general, the dose is calculated according to the following recommendations and is administered once a day:
Children and adolescents with:
Growth hormone deficiency:
0.025 – 0.035 mg / kg of body weight and day,
0.045 – 0.050 mg / kg of body weight and day,
Chronic problems due to the way the kidney works:
0, 045 – 0.050 mg / kg of body weight and day,
Small for gestational age at birth:
0.035 mg / kg of body weight and day. Treatment should be discontinued after the first year of treatment if the growth rate is insufficient,
SHOX gene deficiency:
0.045 – 0.050 mg / kg of body weight and day.
Growth hormone deficiency in adults:
Treatment should be started with a low dose of 0.15-0.30 mg daily. Lower doses may need to be started in overweight or elderly patients. The starting dose can be gradually increased according to your individual requirements. The total daily dose normally does not exceed 1 mg.
Dosage requirements may decrease with age. Women, especially those on oral estrogen replacement therapy, may require higher doses than men.
If you use more Humatrope than you should
If you have injected more Humatrope than you should, check with your doctor.
- If you have injected too much Humatrope 72iu, your blood sugar may initially drop and become very low (hypoglycaemia) and later rise and become very high (hyperglycaemia).
- If too much Humatrope is injected over a long period of time (years), you may experience overgrowth of some parts of your body such as ears, nose, jaw, hands and feet (acromegaly).
In case of overdose or accidental ingestion, immediately consult your doctor or pharmacist or call the Toxicological Information Service, telephone 91 562 04 20 , indicating the medicine and the amount ingested.
If you forget to use Humatrope
Do not inject a double dose to make up for a forgotten dose. Continue with the prescribed dose. If you have forgotten to inject Humatrope and are unsure what to do, check with your doctor.
If you stop taking Humatrope
Ask your doctor before stopping treatment. A premature interruption or discontinuation of Humatrope treatment may affect the success of Humatrope treatment.
If you have any further questions on the use of this medicine, ask your doctor or pharmacist.